Cryotherapy is a process in which patients are exposed to extremely cold temperatures to help treat a variety of conditions. The therapeutic benefits of this therapy range from pain relief and inflammation to improved mental health and healthy skin. Patients may experience the following effects: relaxation, improved sleep, mood elevation, and increased energy. Some patients may even feel euphoric following the session. Cryotherapy treatments are often performed in a clinic or spa environment. The treatment involves exposure to sub-zero temperatures for a short period of time. The treatment is typically safe and lasts between one and three minutes. There are two main types of cryotherapy: whole body cryotherapy and localized cryotherapy. Whole body cryotherapy involves exposure to extremely cold air and can be used for joint pain, muscle aches, and pain associated with inflammatory conditions. Cryotherapy was originally developed by Japanese rheumatologist Dr. Toshima Yamaguchi in 1978. The treatment helps reduce pain and improve mobility by increasing the release of endorphins in the body. It can even reduce the need for prescription medicine. Cryotherapy clinics can be found worldwide. Cryotherapy clinics typically offer treatments for multiple ailments. One type is the cold treatment for prostate cancer, which uses liquid nitrogen to kill cancer cells. Another method uses a cryoprobe inserted through a small incision. The doctor may use ultrasound imaging to guide the probe to the tissue. The patient is usually given local anesthesia before the treatment. Some patients may also require general anesthesia.